What does rs53576 mean?

rs53576 is a silent G to A change in the oxytocin receptor (OXTR) gene. The blog Not Exactly Rocket Science discusses that Americans with (G;G) tend to be more sensitive parents, more empathetic and less lonely than those with an ‘A’.

What is the difference between penetrance and expressivity?

Penetrance and Expressivity. Variable expressivity refers to the range of signs and symptoms that can occur in different people with the same genetic condition. As with reduced penetrance, variable expressivity is probably caused by a combination of genetic, environmental, and lifestyle factors, most of which have not been identified.

Is rs53576 a lack of empathy?

Lack of empathy? rs53576 is a silent G to A change in the oxytocin receptor (OXTR) gene. Studies have demonstrated that individuals with the G allele are more empathetic, feel less lonely, employ more sensitive parenting techniques, and have lower rates of autism (discussed in [ PMID 20724662 ])

Does polydactyly have reduced penetrance and variable expressivity?

Back to the polydactyly example, an extra digit may occur on one or more appendages. The digit can be full size or just a stub. Hence, this allele has reduced penetrance as well as variable expressivity. Variable expressivity refers to the range of signs and symptoms that can occur in different people with the same genetic condition.

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