What is collagenous colitis (cc)?

Collagenous colitis (CC) is a condition that affects your large intestine. It leads to episodes of watery diarrhea and belly pain. Your large intestine is part of your digestive (gastrointestinal or GI) tract. The GI tract goes from your mouth all the way to your rectal opening.

What are the different types of microscopic colitis?

Microscopic colitis is a type of colitis that’s best identified by looking at colon cells under a microscope. The main subtypes of microscopic colitis are collagenous colitis and lymphocytic colitis. In collagenous colitis, a thick layer of collagen — a type of connective protein — forms within the colon tissue.

Is surgery a typical treatment for collagenous colitis?

It’s not a typical treatment for collagenous colitis. The most common types of surgery for collagenous colitis include: colectomy, which means removing all or part of the colon. ileostomy, which means creating an opening in the abdomen after a colectomy.

Can medications cause microscopic colitis and collagenous colitis?

Other studies indicate that these medications also trigger microscopic colitis and collagenous colitis. According to a 2021 study, if these medications are associated with increased rates of microscopic colitis and collagenous colitis, it may be because they make diarrhea worse.

Is sursurgery the best treatment for collagenous colitis?

Surgery is usually reserved for extreme cases. It’s not a typical treatment for collagenous colitis. Collagenous colitis doesn’t cause blood in your stool, increase your risk of colon cancer, or have any effect on life expectancy.

What is the pathogenesis of chronic diarrhea in lymphocytic and collagenous colitis?

The pathogenesis of chronic diarrhea in lymphocytic and collagenous colitis is multifactorial. Diarrhea may result from net fluid secretion in the colon from decreased absorption due to epithelial surface damage and deposition of collagen along with a normal rate of fluid secretion into the lumen from intact crypts.